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  • What are SARMS?

    Hormones are naturally occurring chemical messengers that our bodies use to deliver instructions to our cells through hormone receptors.  SARMS is the acronym for Selective Androgen Receptor Modulators which is a synthetic hormone that is similar to testosterone.

    Most of us have a general idea what testosterone is, but specifically testosterone is an androgen hormone that our bodies naturally produce that causes males to have a deeper voice, grow facial hair, and thin out and develop muscle.

     

    SARMS Act Differently than Testosterone

    SARMS mimic testosterone except where testosterone is not selective and binds to all androgen receptors, SARMS are selective and bind specifically to muscle and bone.  In order to prevent overproduction or imbalances,our bodies naturally regulate androgen production.  Testosterone shots or patches that introduce extra testosterone to the body can cause hair loss, enlarged prostate, and shuts down natural testosterone production due to the bodies natural regulation process.  Body builders and athletes would use testosterone for extra gains.  However, pro-hormones including testosterone were banned so people started looking at SARMS.

     

    SARMS Have Been Studied for Therapeutic Benefits

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  • What is Bacteriostatic Water? Is it Just Sterile Water?

     

    Are Bacteriostatic Water and sterile water the same thing? Some people believe they can replace Bacteriostatic Water with sterile water and get the same results, but while the two sources of liquid are very similar they are not the same and cannot be used interchangeably. Read the instructions carefully for the medication or chemical you are mixing or diluting with water to ensure you are using the correct form: Bacteriostatic Water or sterile water.

     

    Bacteriostatic Water

    Bacteriostatic Water (BW) contains .9% benzyl alcohol and a pH of 5.7. Bacteriostatic Water is used to dilute and dissolve medications that will be administered via intravenous, intramuscular, or subcutaneous injection. The alcohol in the water prevents the growth of many forms of bacteria to prevent infections caused from the injection. BW is not used for infants under four weeks old because the benzyl alcohol is toxic and can cause blood pressure fluctuations.

    Bacteriostatic Water is packaged in 30 mL plastic vials that have undergone animal testing to ensure their safety. This plastic vial does not require a vapor barrier in order to maintain the correct volume. Due to the benzyl alcohol, you can use Bacteriostatic Water for more than one injection within a month. BW water should be used within 28 days of opening the vial, although the preservatives found in the BW will keep it safely up to 30 days.

     

    Sterile Water

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  • LGD-4033 SARM

    Selective Androgen Receptor Modulators (SARMS) are a class of drugs that are manufactured to mimic natural testosterone.  There are a multitude of SARMS that have been developed for the treatment of various conditions including osteoporosis, heart disease, and degenerative muscle loss.  At this time SARMS are only being used for research purposes and have not been evaluated or proven safe for human use.  However, there is a lot of speculation that SARMS could have potential benefits.  

    But what exactly is an androgen receptor modulator you might be asking.  Essentially androgens help to build muscle.  Androgens receptors allow us to accept or bind hormones to our cells.  When we add the “selective” piece to it, we are saying that the androgens will bind or do good where we want it to and not cause harm where we don't want.  One such SARM that is being studied is LGD-4033 which is also called Anabolicum.

     

    What is LGD-4033?

    LGD-4033 is a synthetic drug that works by selectively targeting androgen receptors.  The selectivity is what sets it apart from anabolic type drugs.  While steroids can be harmful to the prostate and other bodily systems, LGD-4003 has been studied to specifically target muscles and bones, thus not causing damage to subjects overall health.  Clinical studies of LGD-4033 have shown that it has the potential to help improve the development of lean muscle mass, increase overall strength, help decrease body fat, and works to heal muscles and joint damage.

     

    Studies of LGD-4033

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  • GHRP-6 vs GHRP-2

    Growth Hormone Releasing Peptides (GHRP) are designed to stimulate the release of growth hormone. GHRP's are in a chemical class of growth hormones known as synthetics.  GHRP does not occur naturally in living things but triggers the release human growth hormone which is a naturally occurring peptide.  Through scientific studies we have begun to understand how GHRP's work in the body and how they could be beneficial in treating natural hormone deficiencies.

    GHRP specifically is composed of six amino acids that create a polypeptide chain.  While stimulating the release of growth hormone (GH) from the pituitary gland, it also stimulates ghrelin.  Ghrelin is produced in the stomach and is a secretion of the growth hormone which regulates hunger. Natural ghrelin production increases at times of fasting and when the body is expecting food.  Understanding this is important when comparing different GHRP's.

    Two of the most common GHRP's are GHRP-6 and GHRP-2.  While they are similar in many ways, they have differences that set them apart from one another.

     

    Similarities of GHRP-6 & GHRP-2

    Both GHRP-6 and GHRP-2 have shown these similar positive effects in scientific studies:

    • an improvement in more rapid cellular repair
    • repair of and an increase in collagen production
    • a reduction in overall body fat
    • better and more restorative sleep patterns

     

    Both also share a few negative effects:
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  • Buy TB-500 for Scientific Research

     Amino acids are found in plants, animals and humans and are the building blocks of most living creatures.  When amino acids combine they form proteins, the thing that binds the amino acid together is called a peptide.   This is a basic scientific concept and while we don't need to get into all of the intricate details, it's helpful to understand the gist of how it works.
    Amino Acids help living creatures grow, break down food, provide energy and repair tissue.  While these amino acids, proteins and peptides occur naturally in living things, scientist have discovered ways to mimic these proteins and have created synthetic versions of many.  Having a synthetic version of a natural protein is important in scientific research in that it helps us to understand how cells function and allows for development of therapeutic drugs to treat certain conditions.  One such synthetic version of a natural protein is TB-500 which is a small piece of the Thymosin Beta 4 peptide chain.

     

    What is Thymosin Beta 4?

    Thymosin Beta 4 is an anti-inflammatory peptide found in all cells. It is a protein made up of 43 amino acids.  It's basic function is to promote healing of of tendons, muscles, ligaments, skin, the heart, and lungs.  It does this through the creation of new blood and muscle cells. This can help to increase flexibility, enhance range of motion, and even repair damaged  heart tissue that occurs due to a heart attack.

    Thymosin Beta 4 is different from other repair type hormone factors in that it, has a low molecular weight, can travel long distances through tissue, promotes endothelial and keratinocyte migration and does not bind to the extracellular matrix.

     

    What is TB-500?

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  • What to Look for When Buying Research Peptides Online

     As with anything you buy online, you want to make sure you are getting the best product from a reputable company.  This is no different when considering purchasing research peptides online.  However, you want to be even more diligent with research peptides because unlike a replacement power cord for your iPhone, or a new piece of gym equipment where a knockoff won't harm anyone, inferior research peptides could affect the quality and accuracy of your experiment results.  There are several ways to check to see if an online research peptide company is offering a pure, quality product.

     

    Online Reviews

    One of the easiest ways to check a company’s reputation is to read online reviews from other consumers.  It's the age old concept of word-of-mouth gone digital.  While the companies own website is a great source to check ratings and reviews, they often control the content and aren't likely to leave overly negative reviews on their page.  If the company has a Facebook page who's setting allows reviews, this is more accurate picture of the company.  Facebook settings do not allow page owners to remove negative reviews without also disabling positive ones.  Even better is to do a general online search for the company.  You can often find blog posts, forums, and social media postings about the research peptides you are interested in purchasing.  If the reviews you find in general on the internet match those on the company’s website, that's a great sign.  However, if there is a huge discrepancy in the reviews, beware.

     

    Product Guarantees
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  • What is GW 1516?

    GW 1516, also known as GW 501,516 or GSK-516, or Endurobol, is a selective activator of the PPARδ gene which is involved in building and regulating muscles. The research peptide was invented through a collaboration of GlaxoSmithKline and Ligand Pharmaceuticals, originally thought to be a candidate for drug treatment of cardiovascular and metabolic diseases. GW 1516 helps burn fat rather than sugar or muscle fibers, and has been shown in a number of research studies to increase endurance and physical fitness. It stimulates glucose uptake for fat burning.  Like with any synthetic hormone it has its positives and negatives.  GW 1516 has been used in many studies of rodents, including mice and rats, as well as humans.  However, at this time, GW 1516 is available for research purposes only.

     

    GW 1516 Scientific Information

     

    Scientific Formula: C21H18F3NO3S2

    IUPAC name: {4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid

     

    GW 1516 in the 1990's

    In the 1990's, drug manufacturer GlaxoSmithKline (GSK) thought that GW 1516 could be a cure for obesity, diabetes, and cardiovascular disease.  They began phase I and II trials on human subjects that showed positive results.  However, they were also doing studies on rats and in those studies, they found that high doses of GW 1516 caused cancer in many organs and at rapid rates - and so they stopped developing and testing GW 1516 for human use.
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  • IGF 1 – LR3 in a Nutshell

    IGF 1– LR3 is a synthetic hormone that has the same properties of naturally occurring insulin.  The letters are short for Insulin-like Growth Factor – 1 Long Arg3, the Arg3 or 3 being representative of arginine being in the 3rd position of the amino acid sequence.  IGF 1- LR3 was created to increase the activity of the growth hormone as it mimics the structure of insulin.

    IGF 1 – LR3 has 83 amino acids, represented in this manner:  MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA.  Amino acids are the foundation of proteins which living things thrive on.  They transport nutrients to muscles which are essential to aiding in repair of damaged tissue.

    There have been many scientific studies of the benefits of IGF 1 – LR3 and it is currently available for research purposes only.

     

    IGF 1 – LR3 and Muscle Fibers

    As we age we naturally lose muscle fiber and our connective tissue deteriorates because our supply of growth hormone and insulin decreases.  In studies of rats, it was shown that injecting IGF 1 – LR3 prevented the deterioration of muscle fibers due to age.  In those that were injected, they showed the same speed and power at 27 months old as they did at 6 months old.  Age related muscle atrophy did not seem to set in.  It can be assumed that larger mammals and perhaps humans would have similar results.
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