GW-501516 5MG X 30ml
GW-501516 (also known as GW-501,516,GW1516 or GSK-516) is a PPAR***948; modulator compound being investigated for drug use by GlaxoSmithKline.[1][2] It activates the same pathways activated through exercise, including PPAR***948; and AMP-activated protein kinase. It is being investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW-501516 has a synergistic effect when combined with AICAR: the combination has been shown to significantly increase exercise endurance in animal studies more than either compound alone.
GW-50156 regulates fat burning through a number of widespread mechanisms. it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.
It has been demonstrated at oral doses of 5 mg a day to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. Treatments with GW-501516 have been shown to increase HDL cholesterol by up to 79% in rhesus monkeys and the compound is now undergoing Phase II trials to improve HDL cholesterol in humans.
Application: A selective and potent PPARB agonist
CAS: 317318-70-0
Molecular Weight: 453.5
Molecular Formula: C21H18F3NO3S2
Appearance: Clear
Storage: Room Temperature
Buy GW-501516 5MG X 30ml
Customer Reviews
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5 Stars Review by Danny
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We are a low budget research facility an took a risk with our tight budget in researching the negative and positive effects of this chemical among a few others having never ordered from this site before. Our test showed purity at 99.2%. We are very impressed and thank Geo Peptides for aiding in our studies. 5 Stars! (Posted on 4/4/2023)
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Everything expected Review by Bryan
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With the research still on going the quality still very high from tests and the rats seem to have a high increase of me to metabolic activity which backs up any foregoing studies. I can not say enough about how fast the shipping has been thanks again. (Posted on 4/4/2023)
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Great products Review by Raddacake
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I have been supplying several labs and Geo is always our first choice. Great quality and best overall prices. Very satisfied. (Posted on 4/4/2023)
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Great products Review by Raddacake
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I have been supplying several labs and Geo is always our first choice. Great quality and best overall prices. Very satisfied. (Posted on 4/4/2023)
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good shipping and products Review by shane
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Ordered both this (gw) and ostarine on labor day weekend, package was promptly shipped, USPS did change the delivery date twice, but every once in a while I guess that can happen. I also emailed geo asking about when it could be expected but it somehow magically arrives that day so I was worries for no reason. Haven't had time to test both products yet, or take a purity test, but both products were placed in dark blue bottles which keep light out and came with 2 1 millileter droppers. Both bottles were bubble wrapped and seem to be professionally packaged even though I used a 40 something percent discount that went on that weekend. I will be returning for more Research chems and supplys in a week or two when I have time and money to do so. Thanks geo! (Posted on 4/4/2023)
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